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                <text>This micrograph of a cutaneous biopsy shows Kaposi's sarcoma (KS) at a medium magnification. The skin contains a dense cellular infiltrate, and narrow slit-like vascular spaces that are characteristic in these KS lesions. KS is a cancer that is common in those who have developed the human immunodeficiency virus (HIV), or an AIDS (acquired immunodeficiency syndrome) infection.</text>
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                <text>This micrograph of a skin biopsy reveals some cytoarchitectural signs that are indicative of Kaposi's sarcoma (KS). The dermis contains a dense cellular infiltrate, and narrow slit-like vascular spaces that are characteristic in these KS lesions. KS is a cancer that is common in those who have developed the human immunodeficiency virus (HIV), or an AIDS (acquired immunodeficiency syndrome) infection.</text>
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                <text>This HIV patient has labial and gingival Kaposi's sarcoma secondary to his AIDS infection which included the jawbone. In approximately 7.5-10 percent of AIDS patients display signs of oral Kaposi's sarcoma, and can range in appearance from a small asymptomatic growths that are flat purple-red in color, to larger nodular growths.</text>
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                <text>Kaposi sarcoma on a patient's right heel displaying the familiar characteristic violaceous cutaneous plaques indicative of this disease.&#13;
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                <text>This image depicts the distal left leg and ankle where you can see a Kaposi's sarcoma (KS) cutaneous lesion. Note that a stasis dermatitis lesion due to venous insufficiency, can sometimes be mistaken for a KS lesion.&#13;
Kaposi sarcoma, is a malignant tumor of the lymphatic endothelium caused by the Human herpesvirus 8 (HHV8), i.e., Kaposi's sarcoma-associated herpesvirus (KSHV), and arises from a cancer of the lymphatic endotheial lining. It is characterized by bluish-red cutaneous nodules. Kaposi's sarcoma is thought of as an opportunistic infection, affecting patients whose immune systems have been compromised, as in the case of patients with HIV/AIDS.</text>
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              <text>June 11, 1981, CDC, Parasitic Disease Division, Kaposi's Sarcoma, male, homosexuals, Friedman-Kein, New York City, Brachman, San Francisco, Florida, Toronto, Dr. Kaiser, Dr. Juranek, Dr. Healy, E. histolytica, drug use, immunosuppression, lymphocytes, Pneumocystis carinii pneumonia, autopsy, pneumocystis pneumonia, death certificate, Ladenstein, Hynes, Cline, Marmor, Muggia, CID, CPS, CEH, Epi Program, Dowdle, Carden, Bennett, Gordon, Herrman, Stewart, Ing, Larsen, Curran, Jaffe, Guinan, Bernard, Bradford, VD Control, CPS, Mt. Zion Hospital, Preikskitas, homosexual, men, CMV, San Francisco, Campylobacter, Cryptococcus </text>
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                <text>MEMORANDUM &#13;
&#13;
FROM: D. Juranek, Deputy Director, Parasitic Diseases Division, Center for Infectious Diseases. &#13;
&#13;
TO: The Record&#13;
&#13;
RE: Kaposi's Sarcoma in Male Homosexuals June 5, 1981. &#13;
&#13;
Dr. Freidman-Kein called P. Brachman to discuss 30 cases of Kaposi's Sarcoma diagnosed in New York City over the past 2 years. Further meetings at CDC convened with the conclusion that Dr. Juranek and Dr. Curran meet with Dr. Friedman-Kein in New York City to obtain more detailed information about some of the cases and lay the groundwork for more detailed epidemiological investigations. </text>
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              <text>November 19, 1981, EIS, Task Force, Kaposi's Sarcoma, Opportunistic Infections, Haitian, Lane, CDC, Center for preventive Services, Snider, TBCD, CPS, Miami, Los Angeles, Roisin, New York, epidemiologists, Hensley, pathologists, CNS toxoplasmosis, Pneumocystis carinii pneumonia, Carden, Malison, Haverkos, name, age, sex, residence, diagnosis, status, steroid, comments</text>
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                <text>MEMORANDUM &#13;
&#13;
FROM: H. Haverkos, EIS Officer, Task Force on Kaposi's Sarcoma and Opportunistic Infections. &#13;
&#13;
TO: Members, Task Force on Kaposi's Sarcoma and Opportunistic Infections, J.M. Lane, Director, Center for Preventive Services, D. Snider, Chief, Research and Development Branch, TBCD, CPS. &#13;
&#13;
RE: The Haitian Connection. Why are there cases of Kaposi's Sarcoma in Haitians and plans to research why. cause. &#13;
List of 11 patients cases. </text>
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                <text>CDC/ Dr. Edwin P. Ewing, Jr.</text>
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                <text>This micrograph depicts the histopathologic changes found in a biopsied lymph node indicative of a Kaposi's sarcomatous lesion from a patient with Acquired Immunodeficiency Syndrome, also known as AIDS. Kaposi's sarcoma is a cancer of connective tissues such as cartilage, bone, fat, muscle, and blood vessel. The vast majority of Kaposi's sarcoma cases have developed in association with human immunodeficiency virus (HIV) infection, and the acquired immunodeficiency syndrome (AIDS). The histopathology revealed in this slide includes characteristic erythrocyte-filled, slit-like spaces, and occasional cells containing globules.</text>
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                <text>CDC/ Dr. Edwin P. Ewing, Jr.</text>
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                <text>Kaposi's sarcoma (KS) lesions located over the medial left ankle and foot.&#13;
In more recent years, the vast majority of cases of Kaposi's sarcoma are found in patients with AIDS (acquired immunodeficiency syndrome). The most common site for KS is on the skin, but it may also affect internal organs, particularly the lymph nodes, the lungs and digestive system.</text>
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                <text>CDC/ Dr. Steve Kraus</text>
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                <text>This HIV-positive patient has an intraoral Kaposi's sarcoma lesion with an overlying candidiasis infection. This AIDS patient exhibited a CD4+ T-cell count &lt;200, and a high viral load. Initially, the KS lesions are flattened and red, but as they age they become raised, and darker, tending to a purple coloration.</text>
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                <text>This brown cutaneous nodule represents a Kaposi's sarcoma lesion commonly found in patients with AIDS (acquired immunodeficiency syndrome). Before the onset of the AIDS pandemic, Kaposi's sarcoma was an uncommon malignancy found mainly amongst Mediterranean men, African children and Ashkenazi Jews, but became the most common neoplasm found in those with AIDS.</text>
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