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&#13;
A letter from Public Health Officials in Philadelphia to Margaret Heckler of HHS urging her to reconsider alternative testing sites for the HTLV-III antibody test. A draft of the response to this letter is attached. This draft was sent to Dr. Dowdle to be edited before sending.</text>
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                <text>The U. S. National Archives and Records Administration at Atlanta, 5780 Jonesboro Road, Morrow, GA 30260       www.archives.gov/atlanta</text>
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                <text>HTLV-III ANTIBODY TESTING: Pilot Program </text>
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                <text>MEMORANDUM&#13;
&#13;
TO: See Distribution List, Drs. Curran, Lamotte, Getchell, et al &#13;
&#13;
FROM: Chief, AIDS Diagnostics Laboratory &#13;
&#13;
RE: HTLV-III Antibody Testing: Results of Pilot Program</text>
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                <text>The U. S. National Archives and Records Administration at Atlanta, 5780 Jonesboro Road, Morrow, GA 30260       www.archives.gov/atlanta</text>
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                <text>HTLV-III SEROPREVALENCE: Kinshasa</text>
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                <text>LETTER&#13;
&#13;
TO: Dr. Curran&#13;
&#13;
FROM: Dr. Mann&#13;
&#13;
RE: The Household Study&#13;
HTLV-III Seroprevalence in Case and Control Households in Kinshasa, Zaire: Evidence for Transmission within Households, which is attached. </text>
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                <text>The U. S. National Archives and Records Administration at Atlanta, 5780 Jonesboro Road, Morrow, GA 30260       www.archives.gov/atlanta</text>
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                <text>HTLV-III/LAV PRECAUTIONS: Prisoner Health </text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="69655">
                <text>MEMORANDUM&#13;
&#13;
TO: Assistant Director for Medical Science, CID &#13;
&#13;
FROM: Assistant Director for Medical Science, DVD &#13;
&#13;
RE: Draft 12/6/85: HTLV-III/LAV Precautions in Correctional Care Facilities. This memo regarded how prisons/jails were to handle inmates who also tested positive for the antibodies.</text>
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                <text>The U. S. National Archives and Records Administration at Atlanta, 5780 Jonesboro Road, Morrow, GA 30260       www.archives.gov/atlanta</text>
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          <element elementId="41">
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            <description>An account of the resource</description>
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              <elementText elementTextId="69671">
                <text>MEMORANDUM &#13;
&#13;
TO: Dr. James W. Curran &#13;
&#13;
FROM: Gerald Schochetman, Assistant Director for Laboratory Science, AIDS Program, CID [Center for Infectious Disease]&#13;
&#13;
RE: Report on ASTPHLD [Association of State and Territorial Public Health Laboratory Directors] Consensus Conference on HTLV-III/LAV Serology&#13;
Consenus recommendations</text>
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                <text>The U. S. National Archives and Records Administration at Atlanta, 5780 Jonesboro Road, Morrow, GA 30260       www.archives.gov/atlanta</text>
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          <element elementId="41">
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            <description>An account of the resource</description>
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              <elementText elementTextId="70130">
                <text>MEMORANDUM&#13;
&#13;
TO: J. Curran, C. Schable, J. Getchell &#13;
&#13;
FROM: Victor C.W. Tsang and J. Steven McDougal &#13;
&#13;
RE: "Western Blots" for detection of HTLV-III/LAV antibodies&#13;
&#13;
"Western Blot' was a nickname for a relatively new technique called the Enzyme-linked Immunoelectrotransfer Blot (EITB).</text>
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                <text>The U. S. National Archives and Records Administration at Atlanta, 5780 Jonesboro Road, Morrow, GA 30260       www.archives.gov/atlanta</text>
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          <element elementId="40">
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            <description>An account of the resource</description>
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              <elementText elementTextId="66845">
                <text>America Responds to AIDS [ARTA]&#13;
"Huellas Peligrosas" [dangerous tracks]&#13;
&#13;
Prevention; Education; Drug Use; Heroin; </text>
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                <text>Centers for Disease Control and Prevention, Public Health Service, America Responde Al SIDA</text>
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                <text>Fact: At least 50% of sexually active people will get genital human papillomavirus [HPV]. &#13;
&#13;
HPV; STD; Prophylactics.  </text>
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A PDF OF THIS INTERVIEW CAN BE FOUND AT THE TOP OF THIS PAGE.</text>
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                  <text>&lt;div class="landing"&gt;
&lt;p&gt;Smallpox disease was declared eradicated in 1980, the result of a collaborative global campaign. To date, it is the only disease affecting humans to be eradicated from the world. Global eradication of smallpox ranks among the great achievements of humankind. Gone, through determined human effort, is a disease which has brought death to millions, frequently altering the course of history, and traveling through the centuries to every part of the world.  &lt;/p&gt;
&lt;p&gt;The vital contributions made by the Centers for Disease Control and Prevention are highlighted. Official government correspondence, meeting transcripts, policy statements, surveillance reports and mortality statistics tell a part of that story. Adding depth to these traditional archives are the personal stories of the public health pioneers who worked tirelessly on the frontlines of the smallpox eradication campaign.&lt;/p&gt;
&lt;p&gt;The links above connect you to a database of oral histories, photographs, documents, and other media.&lt;/p&gt;
&lt;p&gt;Use of this information is free, but please see &lt;strong&gt;“About this Site”&lt;/strong&gt; for guidance on how to acknowledge the sources of the information used&lt;/p&gt;
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              <text>&lt;pre&gt;&lt;strong&gt;
 Interview Transcript
&lt;/strong&gt;
This is an interview with Deane Hutchins about his activities in the West
Africa Smallpox Eradication Project. The interview is being conducted at
the Centers for Disease Control and Prevention in Atlanta, Georgia, on July
14, 2006, as a part of the 40th reunion of the West African Smallpox
Eradication Project, to mark the launch of the project. The interviewer is
Laura Harrar.

Harrar:     I noted in reading your bio that you were involved in private
           practice in Boothbay Harbor and then taught at the University of
           Maine. So how did you even begin to think about taking a leave
           of absence to join the Smallpox Eradication Program?
Hutchins:   While at the University of Maine, I was the Director of
           Clinical Services at the Student Health Center, and I what I
           thought was influenza. I knew D. A. Henderson [Donald A.
           Henderson] because he was my classmate in medical school, and I
           knew he'd been on the surveillance program for influenza. So I
           called him up and said, "D. A., are you interested in some
           throat washings of influenza?" And D. A. said, "No, not really,"
           he said, "but would you like to go to Africa?"
                 My wife and I had never talked about this. I went home
           that noon and talked with her and said I'd seen D. A. She said,
           "What did you talk about?" and I said, "Nothing in particular.
           He asked me if I wanted to go to Africa," and she said, "What
           did you tell him?"
                 I said, "I told him I would call him back."
                 My daughter was home from school, and she went to school
           and told her teacher we were going to Africa. Within 2 days, I
           had called D. A. back and said, "Yes, we'd like to go."
                 I got a leave of absence from the university for 2 years.
           Now, universities don't like to give a 2-year release, but the
           president of the university had been overseas himself and knew
           that it was a 2-year assignment. So I got the leave of absence,
           and we made up our mind and, in July, we came down to CDC and
           were on our way.
Harrar:     I noted that you had a major in zoology in your earlier years.
Hutchins:   Yes. Zoology was just part of the premedical course that we
           took.
Harrar:     And why do you think D. A. tapped you to do this? Had you ever
           imagined that you would be working abroad in public health?
Hutchins:   No. I'd done a few surveys at the university when they had
           their usual food outbreaks and tracked that down, but nothing
           really formal about epidemiology. As I mentioned, I worked with
           D.A. in the same room with the dissecting tables in medical
           school, so I knew him well.
Harrar:     Had you ever imagined that you would work abroad?
Hutchins:   Not in particular. I'd been overseas during World War II, but
           nothing beyond that.
Harrar:     Okay. So you can blame all of this on D.A.
Hutchins:   Blame it on D.A.
Harrar:     Okay, all right. Tell me a little bit about your family at the
           time. Were they excited about this? Was there just the one
           daughter?
Hutchins:   We'd never considered going overseas. My wife was excited about
           it; all 4 daughters were excited about it. And had there been
           one dissent, I'm sure we'd have thought that we shouldn't do it.
           But we decided to go and never regretted it at all.
Harrar:     Would you call your family adventurous and outgoing and
           curious?
Hutchins:   I guess the family probably was curious and was moderately
           outgoing. They had a good time.
Harrar:     What was the range of your daughters' ages at this point?
Hutchins:   The oldest one was 14; the youngest was probably 7.
Harrar:     So, start with the phone call from D. A. Henderson, and tell me
           what happened then, how you got yourself and your family to
           Africa.
Hutchins:   Well, we started preparing to go to Africa, and come June, we
           packed up our Volkswagen, packed up the car, and drove to
           Atlanta.
                 Ion the humorous side of things, we sent our Volkswagen
           bus in June to Nigeria, and we received it the next February,
           which was par for the course.
Harrar:     And so, did you need to send an enormous boatload of goods?
Hutchins:   Yes. We took a lot of things. We had 2 shipments. We had an air
           shipment of limited pounds, and then we had sea freight, in
           which you could take most anything you wanted. We read books to
           find out what we should take.
                 Air freight got there just before Christmas, and we left
           in October. Sea freight didn't get there until sometime in the
           spring.
Harrar:     Was it a pretty big culture shock for you and your family? Talk
           to me about the language issues and some of the cultural changes
           that they had to get used to.
Hutchins:   The cultural shock hit us, I think, the worst right in Lagos,
           which is a capital city. From the airport into the center of the
           city, it's pretty raw. The smells are terrible, as you may well
           remember. It wasn't unusual to see a dead body on the street,
           and it would stay there for a day or 2.
                 Most of the people we dealt with could speak English, so
           that wasn't a big problem. When we got up to Kaduna in northern
           Nigeria, we did try to pick up the local language, Hausa, enough
           so that we could say good morning, how are you, where's the
           bathroom, how do I get home, what time is it, and that type of
           thing.
Harrar:     Would you say that you were welcomed by the local people?
Hutchins:   Definitely. The local people were very nice. I never felt
           uncomfortable. And this was right before the Biafran War had
           started. But about 2 weeks before we went to Kaduna, they'd
           killed about 30,000 Ibo people who were living up there. So
           you'd go by these houses that were strictly empty and burned
           out, and we didn't realize the significance of it at the time,
           but, in retrospect, it was a little bit scary.
Harrar:     How did you and your wife feel about this once you got there
           and you realized what you had brought your family into?
Hutchins:   It was an adventure. I don't think we ever felt uncomfortable.
           There were problems like communications. We were there for 2
           years, and to call the United States, you had to book the call
           ahead of time. Then they would call London, London would call
           New York, then New York would call where you were calling. One
           time I did get through on the telephone. You were limited to 3
           minutes, but my 3 minutes were used up by the time they got
           through, and I could just barely hear my father say, "Hello."
           Then the operator said, "Your time is up." And I said, "Would
           you at least tell him that we're all right?" That was quite an
           experience.
                 We had a telephone in our house all the time we were
           there. It worked just 3 months. The military government took
           over the country. We lived right beside the military governor,
           and I know our telephone number was given to him. But that
           wasn't too bad because no one else had telephones either, so you
           couldn't call anybody.
Harrar:     So, did your family feel isolated at all, do you think?
Hutchins:   I don't think they felt isolated. All of my daughters went to
           school in Kaduna. The second semester, my oldest daughter went
           to an international school down in Ibadan, 400 miles from
           Kaduna. The problem there was that there was just one bridge
           across the Niger River, and this was after fighting had started;
           if they'd blown that bridge, it would have been difficult to get
           to my daughter.
                 Two other daughters went to a missionary school in Joss,
           which was an American school 150 miles from Kaduna. During the
           rainy season, you couldn't drive, so it was a mixed situation.
Harrar:     Transport, yes. And what was your exact role on the Smallpox
           Eradication Program?
Hutchins:   I was the Medical Officer in the Northern Region of Nigeria.
           Two Operations Officers worked with us.
Harrar:     So on a day-to-day basis, describe for me your activities and
           the range of challenges that you had.
Hutchins:   Well, let me tell you a little bit about our office. We lived
           in an ex-Minister of Finance house. This is a Muslim country,
           90% Muslims. So they had a long tunnel that went from the house
           out to the wives' quarters. There were 7 apartments out there, 4
           for wives and 3 for the concubines. Well, since the Minister had
           been kicked out of his house, the Ministry gave it to us to live
           in. We had our offices out in the old wives' quarters, which was
           crude but convenient. It wasn't very nice, but at least it was a
           place where we could sit down.
Harrar:     I thought you were going to say you installed your daughters.
Hutchins:   Well, I did have a kid come up to me and want to buy my
           daughter, but I told him she wasn't for sale. He was serious, I
           think.
Harrar:     On a day-to-day basis, what kinds of things were you involved
           in as a Medical Officer?
Hutchins:   I was concerned about the quality of the organization of the
           eradication program, smallpox reporting, and the vaccinating
           teams. As the reports of smallpox came in, we would investigate
           the outbreak and visit the various smallpox hospitals. That's
           about it, I guess.
Harrar:     Was there a strong sense of collegiality among the people
           working on the effort?
Hutchins:   Yes. We had 3 groups of teams, and each group had about 10
           teams; there were 7 people in each team. So we had well over 100
           Nigerians who were taught to give smallpox vaccinations. Now,
           most of them had not gone beyond 7th grade, but they were
           classified as health workers. We would teach them how to give
           smallpox vaccine with the jet injector and how to take care of
           the vaccine.
                 We stressed very strongly that the vaccine should be kept
           cold at all times. We told the drivers of the trucks to turn
           their refrigerators off-these were kerosene refrigerators-while
           moving along, and when they got to the destination, the first
           thing they should do is turn the refrigerator back on.
                 Well, I came across one truck one day, and it was probably
           100°F or so in the sun. He'd broken down. My first reaction was
           to put my hand down in the freezer to see if it was cold. It was
           hot. So I started giving him a bad time. "But, master," he says,
           "you said to turn it on when I got to my destination," and, of
           course, he was a long way from his destination.
                 But you could tell stories like this end on end.
Harrar:     What do you think were the biggest obstacles that you faced,
           that you had to find a way around?
Hutchins:   Communications, there's no question. For me to get in touch
           with my boss, Stan Foster [Stanley O. Foster], in Lagos was
           almost impossible. And to do it by courier took a long time,
           maybe another week or so, before you'd get an answer back. But
           communication, by all means, was difficult.
                 Transportation of vaccine-getting it from Lagos to Kaduna-
           was also difficult. I remember one time we were having problems
           with this, so we had one of the Americans put it on the plane in
           Lagos. We got to Kaduna, and the vaccine was not there.
           Unbelievable. To this day I don't know where it was. And we're
           talking about several thousand dollars' worth of vaccine.
Harrar:     When you were training the Nigerians, did you also learn things
           from them?
Hutchins:   Oh, yes.
Harrar:     Can you elaborate on that 2-way process?
Hutchins:   I guess, overall, the biggest thing you learn from all
           developing countries is that you're not going to change them a
           whole lot. They've been doing something one way, and they're
           going to continue doing it about the same way.
                 The first morning that we officially vaccinated, I had a
           schedule all made out. At 7:00, the driver is to be there; 8:00,
           we'd move out; at 9:00, we'd start vaccinating. Well, to begin
           with, the drivers didn't show up till after 9:00, and this was
           probably typical of where we worked.
Harrar:     Were there comical things that happened along the way?
Hutchins:   Oh, yes.
                 Well, thievery in developing countries is always a
           problem. We had these kerosene refrigerators, and kerosene was
           worth good money. So I went out one morning, and here's this
           fellow with a 5-gallon can of kerosene in his hand. "Oh," he
           says, "I'm not stealing, I'm putting it back."
                 I guess one of the funniest things that I remember
           concerned Dr. Foege [William H. Foege]. He had been in eastern
           Nigeria, and then the Biafran War broken out, and so they asked
           him to leave. He came up to northern Nigeria, where I was, and
           he said he would like to see some of my teams operating. So I
           gave him a truck and a driver, and he went out. About 3:00 in
           the afternoon, the Minister of Health called me and says,
           "Where's that Dr. Foege? You know, he came up from the east,"
           where, of course, there was fighting. And I said, "He's up-
           country."
                 And so they got the army out and picked him up that
           evening-they wouldn't let him break down his tent-and, under
           armed guard, brought him back to my house. Well, Dr. Foege is a
           very tall person to put in the back of a Land Rover, especially
           with an armed guard on both sides of him. And to hear Bill tell
           the story, he says, "I nudged one of these soldiers and said,
           'Would you mind moving that rifle over? It's hurting my leg.'"
Harrar:     Can't you just hear him saying that?
Hutchins:   Yeah.
Harrar:     Oh, boy. Okay.
                 I understand that you were involved in tracing monkeypox
           to humans in the 1970s.
Hutchins:   Yes. That was in Sierra Leone. I got a call about a case of
           smallpox in a small village. Well, this was after we thought
           smallpox had been eradicated from Sierra Leone. So I went out to
           this village and finally found the case. Clinically, it
           resembled smallpox; you couldn't tell that it wasn't smallpox.
           So I took a brief history and checked to see who had been
           vaccinated against smallpox, and this patient had not been
           vaccinated. I got some samples and sent them back to CDC. Well,
           again, communications. Two or 3 weeks later, I got a cable back
           saying, "This is smallpox. Look for other cases" because you
           can't have one case of smallpox without having another case.
                 So I started looking. After a few days, I got another
           cable from CDC saying, "This is not smallpox. It's monkeypox."
           If you grow it out on the allantoic membrane of chick embryos,
           you can differentiate the 2 viruses.
                 So I went back to the village again and took a better
           history, and, sure enough, this fellow had prepared a monkey to
           eat about 12 days before onset of his illness. This was a tribe
           that ate monkeys. He was the only one who had not been
           vaccinated against smallpox; the rest of the village had been
           vaccinated. This was good evidence that the smallpox vaccination
           also protected him against monkeypox.
Harrar:     Can you tell me a little bit more about the experience in
           Sierra Leone? How did it differ from the experience in Nigeria?
Hutchins:   Well, the day before we left the United States to go to Sierra
           Leone, WHO [World Health Organization] had reported cholera in
           West Africa for the first time, and so I called up CDC to get
           some information on it. I think I talked with Gene Gangarosa or
           one of the fellows in the enteric group, and they gave me what
           information they had on it off the top of their head.
                 I arrived at the airport in Freetown, and reporters were
           there asking how we were going to eradicate cholera; like we had
           eradicated smallpox? Of course, I didn't have any answers for
           them. It's a different disease, and you can't eradicate it like
           that. So I spent most of my time with the cholera program that
           we developed while we were there.
Harrar:     Were there things that you learned about public health in West
           Africa that you have been able to apply in your career since,
           either in some of these international places you worked or back
           in Maine?
Hutchins:   Well, if you see an outbreak of something, you take a different
           approach to it. Most practicing MDs aren't really interested in
           epidemiology, although you became interested in it once you'd
           seen how it can really help.
Harrar:     Is there anything that you wish you could have done differently
           in the way the program was run?
Hutchins:   Well, getting back to the communications, there wasn't too much
           that you could do to improve communications in those days.
           Today, of course, it's so much different.
Harrar:     And how would you say that this experience had an impact on
           your wife and children?
Hutchins:   Well, having lived with a different culture, especially a black
           culture, my kids have no racial bias at all. I don't know if I
           mentioned this before, but my oldest daughter went to school
           with 500 Nigerian schoolgirls, and I think there were 3 other
           expatriates in that school. My daughter has long blonde hair.
           The Nigerian girls were fascinated with this, and they'd come up
           and they'd feel her hair. She learned a lot. And the other kids
           went to various and sundry schools.
Harrar:     So your wife wasn't one who said, "How dare you make a decision
           like that?"
Hutchins:   Well, we had a good time the first 2 years in Nigeria. We went
           back to the States and swore we'd never go overseas again. We
           were back about 3 months, and we decided, "Well, gee, we really
           had a good time," so we went back to Sierra Leone. After Sierra
           Leone, I went with the State Department, taking care of the
           American Embassy personnel in these other countries.
Harrar:     So it turned you into adventurers for the rest of your life.
Hutchins:   Yes. And 2 of my daughters lived overseas after they were
           married.
Harrar:     Did any of them go into health?
Hutchins:   Two are nurses, and one married a doctor.
Harrar:     So, could you comment on the problems of health workers and how
           you could see that getting solved today, I mean from your
           experience seeing the need for trained health personnel?
Hutchins:   I realized that you could train uneducated people to do a
           health program. For example, these vaccinators that we had had
           very little education. Sterile technique was still unheard of,
           and we didn't really use much sterile technique. We did not
           clean off arms before people were vaccinated. We told the
           vaccinators that if they dropped the nozzle of the jet injector
           on the ground, clean it off with some alcohol or something. They
           would just brush it off and put it back on.
                 We did studies to see if there were any adverse effects,
           and there was no significant increase in infections from this
           lack of sterile technique.
Harrar:     And do you think that people can be trained who maybe haven't
           had an advanced education to do many of the tasks of public
           health?
Hutchins:   Yes. Especially something that's repetitive can be taught to
           most anyone. Matter of fact, there are places in West Africa now
           where they teach local people to do eye surgery. You know, it's
           one simple procedure, but they do it, and they have very good
           success with it.
Harrar:     I've heard it said, too, that if one wanted to really solve the
           problem of maternal mortality, if you could get some basic
           anesthesia capacity and some basic cesarean-section capacity,
           you could do an awful lot in field hospitals to save women's
           lives.
Hutchins:   Yes. I think there are places where they've taught the local
           technician to do cesarean sections. It's not that difficult.
           Now, if they run into problems, well, that is a problem, and
           they probably couldn't solve it. But 9 out of 10 go along as
           planned.
Harrar:     Better than obstructed labor?
Hutchins:   Yes.
Harrar:     Is there anything I can ask you that you haven't had a chance
           to speak about that you would like to?
Hutchins:   Well, it was a great experience. I would not recommend it to
           anyone if one member of the family didn't want to go overseas.
           As I said, I worked for the State Department Medical Program
           overseas afterwards. I saw some families that were sent over
           there and there'd be one dissenting family, and invariably that
           whole family was unhappy. They either had to be shipped out or
           would quit.
Harrar:     But, fortunately, you had a family full of adventurous people
           and curious people.
Hutchins:   Yes. Our kids were great, and my wife was great, and we had a
           good time.
Harrar:     Well, thank you so much. I really appreciate it.
                                    # # #
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&lt;p&gt;The vital contributions made by the Centers for Disease Control and Prevention are highlighted. Official government correspondence, meeting transcripts, policy statements, surveillance reports and mortality statistics tell a part of that story. Adding depth to these traditional archives are the personal stories of the public health pioneers who worked tirelessly on the frontlines of the smallpox eradication campaign.&lt;/p&gt;
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HIV @ WORK: More people are living and working with HIV than ever before.  College grad, on the fast track, rainmaker potential, good with people, living with HIV.  HIV hasn't gone away. Neither have the complex HR issues it raises. Can you handle discrimination and return-to-work questions? Or protect employee morale and productivity? Be prepared. Add HIV/AIDS to your employee health and wellness programs and include it in all relevant workplace policies. After all, taking care of people is taking care of business. Get free workplace policy and education information. Check www.hivatwork.org. Or call 1-800-458-5231.  HIV is still in business.&#13;
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