Stanley Foster Oral History

Stanley Foster interviewed by Victoria Harden
July 14, 2006

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Dr, Stanley Foster traces his early years and interest in international health. Describes his recruitment into the EIS and subsequent assignment to Lagos, Nigeria as the Epidemiologist for Nigeria in the Smallpox Eradication Program. Following that he was assigned to Bangladesh's smallpox program and then became the Project Director for the Combating Childhood Communicable Diseases (CCCD) project at CDC.

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Interview Transcript
	   
This is an interview with Dr. Stanley Foster about his activities in the
West Africa Smallpox Eradication Project. The interview is being conducted
at the Centers for Disease Control and Prevention as a part of the 40th
anniversary observance of the launching of the West Africa program. The
date is July 14, 2006, and the interviewer is Victoria Harden.

Harden:     Dr. Foster, would you begin by just briefly describing your
           childhood and your growing up, and who made you who you are.
Foster:          Okay. I grew up in Melrose, Massachusetts. My family was
           very religious. My father died when I was 9 years old, and one
           of the things that happened soon after that was I met Gordon
           Seagrave. He was the famous missionary surgeon whose Burmese
           nurses provided the medical care to Stillwell's troops during
           World War II. And he became my role model. From that stage on, I
           was going to be a doctor. I went to Williams College and then
           went on the University of Rochester.
                 I think the connection to CDC was through D.A. [Donald A.
           Henderson], who also graduated from Rochester, as did Deane
           Hutchins. At that time, in early '62, they were drafting
           doctors, so I decided I'd rather come to CDC than go to the
           Army, so I came here. One of the interesting things that sort of
           started it off was that with 2 "F" names, Bill Foege [William H.
           Foege] and I sat next to each other in the EIS class of '62. I
           was assigned to the Indian Health Service in Arizona and carried
           out 18 epidemiologic studies. My basic assignment was for
           trachoma. At that time, about 20% of the Indian children had
           trachoma.
Harden:     Had you specialized in infectious diseases or anything in your
           medical training?
Foster:     Internal medicine was my field. And, as was often the case,
           Alex [Alexander Langmuir] would try to seduce officers he wanted
           to stay. He sent me to Bolivia to investigate an outbreak of
           conjunctivitis in Peace Corps volunteers. I came back to my home
           in Phoenix, got to Atlanta at about 3:00 in the morning, and at
           6:00 in the morning I was on a plane back to Phoenix and on the
           way to the Truk Islands in the South Pacific to investigate an
           outbreak of diarrhea with Palmer Beasley.
                 The assignment was an epidemiologist's paradise because a
           boat would only go out to an island once a month. You would know
           the entry point, and there would be a health worker there who
           would write down the cases and the names. It was a great
           epidemic. And the pattern of transmission was that of influenza,
           but the disease was diarrhea. We brought back the specimens, and
           the lab tested them out. They couldn't come up with an agent. We
           tried to write up the article several times, but without an
           agent, we couldn't. Twelve years later, when I came back from
           Bangladesh in '76, the lab called me and said, "We just found
           out what your '64 outbreak was. It was a rotavirus."
Harden:     Rotavirus. Ah.
Foster:          So we pulled out the article, finished it, and got it
           published.
Harden:     So you were doing epidemiology up until 1966?
Foster:          Well, no, that's not quite true. I did my EIS training
           from '62 to '64. Then I left CDC and went back to Rochester for
           a year of residency. Then I went to the University of California
           in San Francisco and did a fellowship in pulmonary disease. I
           probably would have stayed on in San Francisco in pulmonary
           disease, but I got the call from D.A., saying, "Do you want to
           go to Africa and get rid of smallpox?" My wife and I thought
           about it, and we decided after 24 hours that was right. We had 3
           kids at the time, and I think one of the things we need to
           discuss is wives and kids.
Harden:     Yes.
Foster:          In terms of the impact of those experiences on the kids.
           Three or 4 of my kids' careers developed out of experiences with
           smallpox. My oldest son was interested in traditional medicines,
           and he now does Internet work in China. My second son, when he
           was in the 8th grade in Dhaka, Bangladesh, did a study of
           rickshaw drivers and how much of their income they spent on
           food. Now he's the chair of the Department of Economics at
           Brown. My third son got his start, really, in 1974 in
           Bangladesh, when we had tremendous floods and a famine. People
           were dying on the streets in front of our house. And he decided
           to go into medicine. I had no knowledge of the impact that the
           famine had on him until I read his Peace Corps application. And
           then I understood that that experience, back in '74, was the
           major event that sent him into medicine.
Harden:     This is very interesting. You said you came from a religious
           family. Were they missionaries or ministers?
Foster:          No, my wife's folks are missionaries. They went to
           Guatemala on their honeymoon. And her mother was interesting.
           She refused to go as a missionary wife. She said she'd only go
           as a missionary, and that was back in the '20s. They went down
           to Guatemala and learned Spanish. Then they learned Mayan and
           put the Mayan writing into a written language. And then they
           translated the New Testament. They had a school and a clinic.
           They stayed there for 45 years. Every year or 2, my wife and I
           go back to that same town. My wife is fluent in the Mam
           language. We have a nurse we work with, and she tells us what
           she wants us to teach.
Harden:     I'm interested in this streak of idealism.
Foster:          Oh, you should get a copy of my college caricature. I have
           a digitalized copy. It shows me sitting in a pot in Africa, with
           the pygmies standing around. "Bless this food to our use" and
           "Dr. Stanley, I presume" written at the bottom. I did have a
           missionary bent at that point in time.
Harden:     I'm seeing a different type of person who has been involved
           here at CDC with the smallpox program than what I have seen with
           investigators at NIH [the National Institutes of Health] in
           terms of the things that motivated them to go into research.
           Let's talk about once you were recruited into the program. They
           asked you apparently to recruit others, as well. And you
           mentioned that the recruitment of this 1 person.
Foster:          Andy Agle [Andrew N. Agle].
Harden:     . . .was interesting?
Foster:          Yes, it was very interesting. Andy was a public health
           advisor and a good mechanic. I remember, I met him at a building
           in San Francisco. He walked in, and he said, "I saw this
           advertisement that you wanted a public health person who spoke
           French and was a good mechanic, and I knew you needed me." That
           was it.
Harden:     Very confident.
Foster:          Yes, he was, there was no question about it. Andy turned
           out to be one of the best. He worked for a long time in West
           Africa; then he was working with smallpox in Afghanistan. He was
           getting bored with Afghanistan, and I brought him to Bangladesh.
           Then he worked for many years at the Carter Center and was very
           close to [President] Jimmy Carter. He did a lot of agricultural
           stuff and really worked incredibly well with the Carter Center.
           And then he took a job in Nigeria. He died about a year ago.
Harden:     Initially, you were the medical officer in Nigeria. Would you
           tell me which region you were in, and what you found?
Foster:          Well, I was responsible for the whole country. At that
           time, Nigeria had 4 regions. the West, the Midwest, the East,
           and the North. About half of the population was in the North and
           about half in the South. We had Margaret Grigsby and Jim Lewis
           in the western region; Warren Jones was in the Midwest; Bill
           Foege, Dave Thompson [David M. Thompson], and Paul Lichfield
           were in the East; and Deane Hutchins and Vicky Jones [Clara
           Jones] were in the North. And it was a very different program in
           the North than in the South.
Harden:     Would you tell me about that?
Foster:          In the North, the traditional leadership was incredibly
           strong. I remember the first village I went to, Gwadabaw, in
           '66.I got there at 6:00 in the morning, and there were 6,000 men
           in a line. We vaccinated the men, and then they went home, and
           then the women came out. Well, for the women to come out was a
           big social occasion. They really didn't want to go back in.
                 But I learned something that day, which was very
           interesting. It was a big district, and I told the district head
           that we should have 3 vaccination sites in his town because it
           would take us too long to do it at 1 site. He said, "I forbid
           you for doing that." He says, "Everybody has to be vaccinated in
           front of me. Nobody will tell me that they were vaccinated if it
           had to be in front of me, whereas if there were 3 sites, they
           could be tell me they were vaccinated when they weren't. The
           Emirs of Sokoto, Katsina, Kaduna, and Kano were very powerful
           people. The Emir of Sokoto would ride around in his Mercedes
           every night, and if there was no petrol, the Mercedes got pushed
           around town. But he was very powerful. So the only thing that
           you had to do in the North was to convince the Emir, and he
           would call in his district heads, and then everything would
           happen. It was easy to get 96%-98% coverage in that region. In
           the South, it was much more difficult. The people would not go
           200 or 300 yards for vaccination. People were much more
           independent in the South. There was not the structure, and it
           made it much more difficult to get people to come for
           vaccination.
Harden:     Why would they not want vaccinations?
Foster:          Well, I think if you go historically back, there was a
           demand for injections. We believe that occurred secondary to the
           yaws program, which gave shots of penicillin to treat yaws. But
           it cured venereal diseases and pneumonia and everything else. So
           injections were always sought after. In the North, the structure
           was such that people would be told to do it and they'd do it. In
           the South, you had to really convince them or use enough
           publicity to get people to come for vaccination. So it was a
           totally different thing.
                 And the epidemiology of measles was different. In the
           North, where the women are in purdah, or where the population
           density was relatively low, the median age of measles was about
           36 months. In Lagos, where you have mothers carrying their
           babies on their backs to market, the median age was around 14
           months, and then that was with a population of 600,000. When I
           went back in the '80s and '90s to Lagos, which now has a
           population of over 10 million and possibly 20 million, the
           median age of measles had dropped even further, to around 8
           months. Controlling measles was impossible.
Harden:     What was the toughest problem you encountered?
Foster:          Oh, the Biafran civil war. I had flown to Benin to see
           Warren Jones there. I got off the plane, and Biafran hijackers
           got on and hijacked the plane. And that plane later was used to
           bomb Lagos. It was very interesting: we believe that they were
           using the passenger plane as a bomber, defusing the bombs, and
           throwing them out the door. We felt that probably the reason
           that the plane exploded was because the bomb went off before it
           got out the door. Of course, they had to find somebody who was
           asleep at their gun to reward for shooting this plane down. That
           was tense, and a lot of people were evacuated.
                 I was talking with Deane Hutchins at lunch. I took the
           kids and my wife up to Kaduna because I thought it was safe. The
           next day, they bombed the Kaduna airport. But one of the
           interesting things at that time, we knew there was no smallpox
           in Biafra; but I was really afraid smallpox would get into
           Biafra. So I convinced the government that the safest thing for
           them to do was to vaccinate a large area around Biafra so that
           the smallpox wouldn't get out of Biafra into Nigeria. That way
           we kept it out. We also vaccinated a lot of children coming
           through the lines. The malnutrition in pockets of Biafra was
           just absolutely terrible. I think the war was really the
           toughest obstacle. The regional office was shattered by the
           bombings in Lagos, and it was not as safe a place as it had been
           before that.
Harden:     How did you get along with your counterparts?
Foster:          Oh, I had the most wonderful counterpart in the world, a
           fellow by the name of Yeme Ademola, who had gone to the Harvard
           School of Public Health. If you go back into the history of the
           smallpox/measles program, USAID [US Agency for International
           Development] wanted to do all the countries except Ghana and
           Nigeria. And Ademola was one of the ones who achieved its
           inclusion in the program He actually went and met with Senator
           Kennedy [John F. Kennedy] to push that.
                 Yeme was just so honest. He looked out for the poor. For
           example, he had a cooperative grain bank, where he would buy
           produce when the price was low, and then they would sell it when
           the price was high. He supported a clinic. He was just an
           absolutely wonderful guy, and he also was my neighbor. So he and
           my wife would often go out and have tea with Yemi and his
           British wife. He also is the subject of the most traumatic part
           of my time in Nigeria. I got a call one night about 3:00 in the
           morning, Rosa, his wife said that he had been attacked. When I
           arrived at the front door, the murderers went out the back door.
           He had been macheted across the neck. I went in and tried to
           save him, but I couldn't. And at that time, I wasn't thinking of
           my wife, who was pregnant. Panicked about me, she started to
           abort. It was a horrible day. And then the next day, the police
           came and wanted to put me under arrest for Yemi's murder. After
           a 6-hour standoff, the American Embassy got me off on account of
           my diplomatic status. So that was the single most traumatic
           event of my years in Nigeria.
                 We had an incredibly interesting team. We had Deane
           Hutchins and Vicki Jones. My favorite story of Vicki was when
           she went out in the field once for 4 or 5 weeks, and she'd
           either broken or forgotten her mirror. When she came back to
           Kaduna and looked at the mirror, she said, "Something's wrong."
           And then she realized it was that her face was white. In other
           words, she'd only seen black faces for 6 weeks. But she was
           wonderful.
                 The teams in the North were also just absolutely
           extraordinary people. They had a driver there. He would know,
           when he went into a village, who you needed to see first, who
           you see second, and who you should see third. He had driven for
           a political figure before that, and he was just good. The teams
           would go, and they could vaccinate with the jet injectors, 8,000-
           10,000 a day. The most I ever remember vaccinating in a day was
           once in the Midwest: with 4 lines we vaccinated 14,000.
Harden:     Wow.
Foster:          I think it's important to put in perspective what Henry
           Gelfand had learned about India. The Indians had vaccination
           numbers greater than the population, but they still had lots of
           smallpox. So Henry Gelfand went out there and did an assessment.
           And he found the vaccinators were vaccinating the schoolchildren
           regularly, so that they could get high numbers of vaccination,
           but coverage was very low. So when we went to West Africa, we
           were absolutely sure that with high coverage (Rafe [Ralph H.
           Henderson] and Don Eddins adapted coverage surveys from the US
           immunization survey to Africa) we would stop smallpox. There was
           no question about it. And that was our strategy, and we were
           absolutely sure that with high coverage with the jet injectors
           and coverage surveys-if we got above 90% coverage, or 95% or
           even better-we'd stop smallpox.
                 Four or 5 major events led to a change in that strategy.
           The first was that when we first arrived in Nigeria, there was a
           smallpox outbreak in eastern Nigeria, in Ogoja, where Bill Foege
           had been a missionary. They had a limited amount of vaccine. But
           by focusing the vaccine on the infected area, they stopped the
           outbreak. The second important thing was a series of spot maps
           that Bill Foege drew. Each year the smallpox would come from the
           North, and there'd be a few outbreaks on the northern border and
           in the East. Then the outbreaks would increase in number and
           frequency, so you could just see it spread southward. And
           although Bill doesn't remember this, I remember Bill sitting on
           the steps, looking at these monthly maps and seeing how the
           smallpox spread. And he raised the question, "If we stop these
           first few outbreaks, will we stop them all?" The third major
           event in the shift in strategy occurred in Abakaliki. (There's a
           nice paper about this by Dave Thompson and Bill.) They'd done a
           coverage survey, and Abakaliki had over 90% coverage. Then all
           of a sudden they had an outbreak of smallpox. The outbreak
           occurred in a religious group that had refused vaccination; I
           think it was called Faith Tabernacle. Smallpox even though the
           coverage in that area was 90%; the small group of unvaccinated
           people was able to sustain an outbreak. The fourth factor was
           the shape of the epidemic curve-a low in September-October and
           epidemic in the early spring. Bill figured it out that every
           chain of transmission in the fall caused 74 cases in the spring.
           He realized that the peak time for surveillance was when the
           chains of transmission were fewest. So, in my opinion, those
           were the major events that shifted the strategy from mass
           vaccination and surveys to surveillance/containment. And that
           was certainly a major shift.
                 And I think, although the disease eradication programs
           were different, when you compare smallpox to malaria, malaria
           was a centrally directed program, and they never really
           responded to the signs of drug resistance, and insect
           resistance, and the program failed. Smallpox was different. The
           program was driven by data collected in the field. We learned
           from our failures and changed strategies to address them.
                 When I teach on lessons learned from smallpox/measles, one
           of the major things is learning from our mistakes, being willing
           to learn from our mistakes. My favorite story on this is about
           Sabour. He was one of my team leaders in Bangladesh. At this
           time, India was free of smallpox, but we were still having
           trouble. And I went up to see Sabour in Mymensingh, near the
           Indian border. If we did everything right, once we found an
           affected village, there should be no cases after 14 days-after 1
           incubation period. So I asked Sabour, "How many outbreaks do you
           have?" And he said, "Sixteen." And I asked him, "How many had
           gone more than 14 days." And he said, "Eleven." Well, this was a
           disaster. The people could've walked those cases across to
           India, where the reward was big, and made a lot of money. And so
           I said to Sabour, "What are you doing?" His response was, "I'm
           doing everything the book says. I'm putting the patient in the
           house; I'm putting a guard at the front door and the back door.
           I have an extra guard at night to keep the guards awake. I am
           making a list of visitors, vaccinating them, and putting them
           under surveillance. I'm vaccinating everybody in the household.
           I'm vaccinating everybody in a half-mile. And I'm searching
           every place in 5 miles." And then, across a cup of tea, an
           incredible smile. And Sabour said, "And today I found out why.
           I'm going in, and I'm asking for a list of visitors. They are
           not giving me the names of relatives who came to visit because
           they don't consider relatives as visitors. And so we added a
           list of relatives to the procedure and solved the problem."
                 I think that this story illustrates one of the main points
           to get at, that a lot of us at CDC who are in leadership
           positions got a lot of credit for smallpox eradication, but it's
           these people who worked 28 days a month in the field, month in
           and month out for 5 years, some of them, who were the real
           heroes of smallpox.
                 The other lesson to get out of this story was the
           importance of giving workers at the field level the indicators
           to assess their own performance. When they didn't meet them,
           they asked why and come up with a solution.
                 There's 1 other similar story from India, which is really
           important. At a critical time in the program in India, things
           were going to hell in a basket in Bihar, and the numbers were
           going up. And the Minister said, "I'm sorry, no more
           surveillance/containment. We're going back to mass vaccination."
           Bill spent the whole weekend with the Minister, trying to
           convince him to continue surveillance/containment. But the
           Minister said he couldn't take the political pressure and he had
           decided that the only solution was to mass-vaccinate. At the
           Monday meeting, the Health Minister of Bihar got up and said,
           "I'm sorry, WHO [the World Health Organization] has recommended
           we continue to do this, but I can't stand the political heat any
           more, so we're going back to mass vaccination." In the back of
           the room, a hand raised. And a man got up and said, "Mister
           Minister, I am a poor country doctor. But when we have a house
           on fire in our village, we direct the water at that house and
           not the whole village." And the Minister said, "You have 1 more
           month." And fortunately over that month things got better, and
           so they continued surveillance/containment. Both of these
           examples illustrate the really major contributions that poorly
           paid and unrecognized field workers made. They really deserve a
           great deal of credit for what went on and the success achieved.
Harden:     But don't you think it was also remarkable that the bureaucracy
           and the people at headquarters were flexible enough to ask for
           and act on that kind of information? Many times you get
           bureaucracies that think they know best, no matter what's coming
           in. I think the synergy was quite remarkable.
      Foster:    Yes. Well, I think that's the main difference between
            smallpox and malaria. When we introduced the reward for
            reporting smallpox in Bangladesh, I introduced a single reward.
            But after about 6 months, only 35% of the public knew about the
            reward. And then all of a sudden, I discovered my mistake. None
            of the health workers were telling the public because they
            didn't want the public to claim the money. So we doubled the
            reward to pay both the health worker and the public, and within
            4 or 5 months, 80% of the country knew about the reward.
Harden:     So getting the word out, and knowing how the culture operates,
           also played a huge role.
Foster:          The Bangladeshi field staff used to say that working for
           the smallpox program was the best form of family planning (they
           were never home) because at least their wives didn't get
           pregnant. As you look at the evolution of
           surveillance/containment in West Africa to the rest of the
           world, it's a steady thing. .Probably the best place it was
           demonstrated was in Sierra Leone. Don Hopkins didn't have enough
           material to do the whole country. So on 1 side he did mass
           vaccination, the other he did surveillance/containment. Smallpox
           stopped in the southeastern area but continued on in the mass
           vaccination area. That proved surveillance/containment worked.
           Secondly, the legacy of surveillance/containment out of West
           Africa clearly was key to the success of global eradication of
           smallpox. Had it not been developed, it is unlikely that we
           would have ever stopped smallpox, in Asia especially.
Harden:     What about the role of the bifurcated needle? In my mind, West
           Africa was the jet injector and Asia was the bifurcated needle.
Foster:          This is not quite true. When we shifted from mass
           vaccination to surveillance/containment, the bifurcated needle
           became the preferred route of immunization. The bifurcated
           needle was developed to vaccinate chickens. It had 2 main
           advantages. It increased the amount of vaccine available 100-
           fold. It only took 1/100 the vaccine required by the multiple
           pressure method, where a drop was put on the skin and the site
           was scarified by pressing a needle parallel to the skin 15
           times. The bifurcated needle take rates were 99% effective
           versus the traditional method's effectivity of 90%-98%.
                 In Bangladesh, the bifurcated needle totally transformed
           containment. We could train a villager to use the bifurcated
           needle in 10-15 minutes. This brought ownership of containment
           to the village and quicker, more effective, control. It also
           solved the problem of getting health workers to spend nights in
           the infected villages, a major problem in the early stages in
           containment in Asia. Once you were hiring vaccinators to
           vaccinate their village, the barrier of the stranger was
           removed, and accommodations in the infected village were
           possible and acceptable.
                 I think we go should back just a little bit, to 1945.
           After World War II, smallpox was endemic in most countries of
           the world, especially in tropical areas, where the liquid
           vaccine was unstable in the heat. So the development of the
           freeze-dried vaccine (you could carry it in your pocket, it
           didn't require refrigeration, and you could mix it up for the
           day and it would be good) was a big thing.
New topic relevant to West African program but not to smallpox
                 And then the initial development of measles vaccine, the
           Edmonston B measles vaccine, it could only be given with gamma
           globulin. And the vaccine was not, at that time, licensed. It
           had been tested in about 20,000 kids. At just about that time, 4
           Ministers of Health visited the States and NIH. Harry Meyer
           happened to talk to them, and one of them got very excited. The
           Minister of Health of Upper Volta said measles was killing 20%
           of the children in Africa and Meyer should come to Upper Volta
           (now Burkino Faso) to test the vaccine there. So the first year,
           Harry went to Upper Volta and tested the vaccine. The vaccine
           proved its safety and efficacy without gamma globulin: that was
           a major step forward. The demand was such that the next year
           they vaccinated 700,000 in Burkina Faso. It was a tremendous
           success medically and politically.
                 Then the United States expanded to the other countries in
           OCCGE [Organization de Coordination et de Cooperation pour la
           Lutte Contre Grandes Endemies] and that was when CDC first
           became involved. Probably the best story about that concerns
           Larry Altman [Lawrence K. Altman]. Larry's now a science writer
           for the New York Times. He was sent out to Mali to address
           problems with the measles program there. One day he sent back a
           cable to Washington that said, "The trucks don't keep the
           vaccine cold." And a cable came back from Washington, "Park in
           the shade." And so Larry sent a cable back, "Send trees."
                 The measles program was a smashing success medically and
           politically. You had 3 parallel channels. You had the smallpox
           channel going on at CDC; you had Harry Meyer, who had proved the
           safety and effectiveness of given multiple vaccines at the same
           time. And then USAID and measles. USAID for some reason thought
           they could vaccinate a fourth of the children the first year, a
           fourth the second, a fourth the third, a fourth the last, and
           they would be done. That was totally wrong. I was talking to
           Dave Sencer about a phone call he got from A.C. Curtis from
           USAID, who called him and said, "What about a measles
           eradication program," and Dave said, "No, it can't be done.
           Measles is only control, Smallpox is eradication. Why don't we
           marry smallpox and measles?" Without measles, there would have
           been no West African Smallpox Eradication measles Control
           Program, no global program, and probably no eradication of
           smallpox. The WHO 1,000-page history of smallpox has several
           flaws, the major one being the order of chapters. They placed
           the West African chapter after India and Bangladesh. Bangladesh
           and India built on the lessons learned in West Africa and
           succeeded because of it
                 While the marriage of smallpox and measles was key to
           smallpox eradication, the effects on measles were short-lived
           because of the lack of infrastructure to maintain vaccination.
           Successful control of measles has only been achieved in the last
           5 years with a new strategy. It should be recognized that Jean
           Roy, the Operations Officer in Benin, has been a key player in
           this success in bringing the League of Red Cross Societies into
           play-resources from the wealthier countries and Red Cross
           volunteers on the ground to mobilize the public.
                 It should also be said that the marriage of smallpox and
           measles was a major barrier between USAID and CDC. USAID felt
           they had been been conned. This was really the basis of a lot of
           the angst between USAID and CDC because essentially USAID paid
           the whole bill.
                 And I was talking to D.A. last night on the phone, trying
           to clarify a few pieces of history, which is always difficult
           with D.A. When the United States first agreed to do smallpox,
           there was a briefing of the US delegation to the WHO Assembly.
           Even the secretary of HHS [Department of Health and Human
           Services; then, it was Health Education and Welfare] was not
           aware of the plan. So then the announcement went out at the
           assembly, from President Lyndon Johnson, that the United States
           would support a smallpox eradication program in West Africa.
           Later, the smallpox/measles marriage took place. Clearly, Dave
           Sencer was a key actor in this. D.A. told me last night-which I
           didn't know-that that press release about smallpox was written
           by Bill Moyers. That was the international Year of Cooperation,
           or something like that. And smallpox eradication and the US
           contribution fit this like a glove from 3 perspectives: science,
           development, and politics.
Harden:     You have mentioned the 2 women who were professionals the West
           African Program. Neither of them is here for the reunion, but
           could you talk about who they were and how exceptional they
           were?
Foster:          Yes. Two very different people. Vicki Jones, young, free
           spirit, guitar-playing, and Margaret Grigsby, an older, African-
           American woman professor at Howard, very prim and proper. I
           remember we had some issues insuring that there was a proper
           latrine arrangement for her when she went to the field. And it
           was difficult in the area that Margaret was in, in terms of
           getting cooperation. Margaret was great. She had her heart and
           soul in the program and bonded well with her African colleagues.
           I do remember the first outbreak I went to in the western
           region. They had isolated the smallpox patients in a cocoa farm,
           and the only people who were allowed to go there were those who
           had the scars of smallpox. This is very, very interesting. On
           the other hand, you have the smallpox cult, Shapona cult, where
           if you didn't want to get smallpox, you paid the priest. If you
           got smallpox and didn't want to die, you paid the priest. And if
           you died, the priest got all of your worldly possessions. So
           they couldn't lose.
                 There are historical accounts, in the 1800s, of priests
           actually infecting people who didn't pay up by putting smallpox
           scabs on sticks going into houses. Actually, I remember the last
           African outbreak I visited, in Togo. A couple of the traditional
           healers were there trying to pick scabs. Fortunately, the scars
           were from a vaccinial modified case, so it was not likely that
           there was much virus left.
Harden:     What did Africa teach you about yourself and about public
health?
Foster:          We were young; we were bright; but we were not bright
           enough to say we couldn't do it. I mean, that was really
           important. In other words, there was never a sense that we
           couldn't succeed. It was a totally different story in
           Bangladesh. But we learned as we went along. We had pretty good
           government response and fairly credible civil service. At least,
           we were paying per diems and that sort of thing, kept people
           working. It was a well-oiled machine. I mean, we had something
           like 80 Dodge trucks in Nigeria. We had lots of spare parts. I
           think the last one I saw running was in the late '80s.
Harden:     What kind of impact do you think the whole West African program
           had on the global eradication program?
Foster:          Had West Africa not succeeded, it's doubtful that the
           global program would have succeeded. I have no question in my
           mind that it laid the foundation, and one of the great
           injustices in the smallpox book is that the West Africa chapter
           is put after India and Bangladesh. This is extremely unfortunate
           and historically incorrect because a lot of the lessons learned
           out of West Africa laid the foundation for what went on in Asia,
           and Ethiopia, and Somalia.
Harden:     Indeed. Is there anything you would change if you were running
           the program all over again?
Foster:          What we did then, we couldn't do now.
Harden:     Say again?
Foster:          What we did then, we couldn't do now.
Harden:     Why?
Foster:          I mean, it was pretty much an expatriate-run operation-
           money-driven, technology-driven. We did not have the proper
           amount of deference to local culture and societies and
           governments.
Harden:     I wondered about that.
Foster:          It was pretty much a technology-driven program. It was
           marvelous in terms of the teams we had. Some of the Operations
           Officers, Dave Bassett for one, George Stroh for another. George
           was driving from Jos down to the South when his motor mounts
           broke, and his motor fell out of his engine. He put the motor
           back in and drove home. I mean, just that kind of ability, to
           react in the field. So that was important.
                 In Asia, several things were key. One was that the monthly
           meetings were incredibly important. People came in, they gave
           their reports, they shared the successes, they shared their
           failures, they got drunk, they sobered up, they got their money,
           they went back to the field. And most of them spent 25-28 days
           in the field. And as I look at CDC people going in the field
           now, they don't do that much any more.
Harden:     Are there any final things that you want to say?
Foster:          The challenges of West Africa were nothing compared to
           what it was in Bangladesh, especially in the floods of 1974,
           when the 2 remaining areas of infection were totally flooded out
           and people went into motion. We went from 89 infected villages
           in October of '74, to 1,500 the following May. We were all
           depressed. We lost it. A wonderful guy, Rangaraj, was my deputy;
           he was the first Indian physician parachutist. He had fought
           with Stillwell in Burma. And every morning, he would say, "It's
           going to be all right. Hang in there." Every day, he was like
           that. There was no rationale for that. Later on, when I was
           working in Somalia, I had a beer with Rangaraj 1 night, and I
           said, "Ranga, how could you have been so optimistic?" He said,
           "I didn't think you had a chance in hell in winning, but when I
           fought with Stillwell in World War II, I learned that if you
           ever thought you'd be dead the next day, you would be dead." So
           it was his military training and his optimism that enabled us to
           keep going, during incredibly difficult times. When I walk into
           an HIV/AIDS village today, I feel Ranga's hands on my shoulder.
           "Hang in there it will be all right."
Harden:     And eventually, to win.
Foster:          Yeah, and eventually to win. And Ranga was incredibly
           important. And there were lots of people like that. In
           Bangladesh, we had 22 nationalities on our staff, and they were
           they best. I mean, they were family. We were all 1 family. The
           monthly meetings were key. Then surveillance got incredibly
           better, and we were able to track things. And we used money. We
           paid $25,000 in rewards starting at $2.50 per report of an
           infected village and increasing to $50 as the number of infected
           villages in Bangladesh decreased. And we learned. For example,
           when we started in Bangladesh, we were having trouble with
           containment until we started hiring people from the village. The
           reason we were failing was because health workers had no place
           to stay in the villages. Once you started hiring villagers to do
           the work, you had a place for your health workers to stay. And
           so there was a tremendous lesson.